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Type: Artigo de periódico
Title: Comparison of 2.5% Sodium Hypochlorite and 2% Chlorhexidine Gel on Oral Bacterial Lipopolysaccharide Reduction from Primarily Infected Root Canals
Author: Gomes, BPFA
Martinho, FC
Vianna, ME
Abstract: Introduction: This clinical study was conducted to compare the efficacy of chemomechanical preparation with 2.5% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX) gel on eliminating oral bacterial lipo-polysaccharide (LPS) in teeth with pulp necrosis and apical periodontitis. Methods: Fifty-four root canals were selected. Samples were collect before (s1) and after chemomechanical preparation (Q). Teeth were randomly divided into groups: GI, 2.5% NaOCl (n = 27) and GII, CHX gel (n = 27). Limulus amebocyte lysate assay was used to quantify endotoxins. Results: Endotoxin was present in 100% of the samples investigated, with a median value of 272 endotoxin units (EU)/mL (GI) and of 152.46 EU/mL (GII). As a result of chemomechanical preparation, LPS content was reduced to a median value of 86 EU/mL (GI) and 85 EU/mL (GII). Higher percentage value of endotoxin reduction was found in GI (P < .05). Conclusions: The 2.5% NaOCl and 2% CHX gel were not effective in eliminating endotoxin from the primarily infected root canals. (I Endod 2009;35:1350-1353)
Subject: Bacteria
oral bacterial LPS
root canal
sodium hypochlorite
Country: EUA
Editor: Elsevier Science Inc
Citation: Journal Of Endodontics. Elsevier Science Inc, v. 35, n. 10, n. 1350, n. 1353, 2009.
Rights: fechado
Identifier DOI: 10.1016/j.joen.2009.06.011
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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