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Type: Artigo de periódico
Title: Clinical Investigation of the Efficacy of Chemomechanical Preparation with Rotary Nickel-Titanium Files for Removal of Endotoxin from Primarily Infected Root Canals
Author: Martinho, FC
Chiesa, WMM
Marinho, ACS
Zaia, AA
Ferraz, CCR
Almeida, JEA
Souza, FJ
Gomes, BPFA
Abstract: Introduction: This clinical study was conducted to investigate the ability of chemomechanical preparation with 25% NaOCl + 17% ethylenediaminetetraacetic acid (EDTA) and rotary nickel-titanium (NiTi) system in removing endotoxin from primary root canal infection with apical periodontitis. Methods: Twenty-one root canals with necrotic pulps were selected. Samples were collected before (s1) and after chemomechanical preparation (s2). The limulus amebocyte lysate (LAL) assay was used to quantify endotoxins. Results: The LAL assay indicated that endotoxins were present in 100% of the root canals investigated (19/19) before (s1) and after chemomechanical preparation (s2). Analyses of the quantitative data revealed that the endotoxin content was significantly reduced at s2 (98.06%) compared with that at Si (P < .05). Conclusions: Our findings indicate that chemomechanical preparation with 2.5% NaOCl + 17% EDTA and rotary NiTi files was effective in reducing endotoxin load in the root canal infection from primarily infected teeth with apical periodontitis. (1 Endod 2010;36:1766-1769)
Subject: EDTA
Mtwo system
root canal
rotary instrumentation
Country: EUA
Editor: Elsevier Science Inc
Citation: Journal Of Endodontics. Elsevier Science Inc, v. 36, n. 11, n. 1766, n. 1769, 2010.
Rights: fechado
Identifier DOI: 10.1016/j.joen.2010.08.019
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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