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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleAssessment of antioxidant and antiproliferative activities and the identification of phenolic compounds of exotic Brazilian fruitspt_BR
dc.contributor.authorMalta, LGpt_BR
dc.contributor.authorTessaro, EPpt_BR
dc.contributor.authorEberlin, Mpt_BR
dc.contributor.authorPastore, GMpt_BR
dc.contributor.authorLiu, RHpt_BR
unicamp.author.emaillucianamalta@yahoo.compt_BR
unicamp.author.emailrl23@cornell.edupt_BR
unicamp.authorMalta, Luciana Gomes Pastore, Glaucia Maria Univ Campinas UNICAMP, Dept Food Sci, Fac Food Engn, Campinas, SP, Brazilpt_BR
unicamp.authorTessaro, Elias Paulo Eberlin, Marcos Univ Campinas UNICAMP, ThoMSon Mass Spectrometry Lab, Inst Chem, Campinas, SP, Brazilpt_BR
unicamp.authorLiu, Rui Hai Cornell Univ, Dept Food Sci, Ithaca, NY 14853 USApt_BR
dc.subjectFruitspt_BR
dc.subjectPhenolicspt_BR
dc.subjectFlavonoidspt_BR
dc.subjectAntioxidant activitypt_BR
dc.subjectAntiproliferative activitypt_BR
dc.subjectESI-TOF-MSpt_BR
dc.subject.wosAnti Proliferative Activitiespt_BR
dc.subject.wosIonization Mass-spectrometrypt_BR
dc.subject.wosCommon Fruitspt_BR
dc.subject.wosIn-vitropt_BR
dc.subject.wosExtractspt_BR
dc.subject.wosAssaypt_BR
dc.subject.wosComponentspt_BR
dc.description.abstractPhenolics including flavonoids are suggested to be the major bioactive compounds contributing to the health benefits of fruits and vegetables. The objective of the study was to determine the total phenolic and flavonoid contents, oxygen radical absorbance capacity (ORAC), peroxyl radical scavenging capacity (PSC), cellular antioxidant activity (CAA) and antiproliferative properties of selected cerrado fruits named gabiroba (Campomanesia cambessedeana Berg), murici (Byrsonoma verbascifolia Rich) and guapeva (Pouteria guardneriana Radlk). Gabiroba fruit showed the highest amount of total phenolics (851.0 +/- 40.7 mg/100 g fruit) and the highest antioxidant activity for both the performed assays (ORAC 8027.5 +/- 378.6 gmol TE/100 g fruit and PSC 2342.5 +/- 48.1 mu mol AAE/100 g fruit). Gabiroba fruit and the pulp of guapeva had the highest antiproliferative capacity with the lowest EC50 40.7 +/- 4.8 mg/mL and 37.9 +/-2.2 mg/mL, respectively. The results for the analyzed fruits for CAA were not significantly different from each other (p < 0.05) (murici 41.3 +/- 17.8; gabiroba 33.9 +/- 18.8 and the pulp of guapeva 23.3 +/- 4.2 mu mol quercetin/100 g fruit). More than 30 phenolic compounds in the pulp of guapeva, gabiroba and murici extracts were identified in the present study using ESI-TOF-MS. These results characterized for the first time the functional activity of selected Brazilian fruits and demonstrated the importance of these fruits from cerrado biome. (C) 2013 Elsevier Ltd. All rights reserved.pt
dc.relation.ispartofFood Research Internationalpt_BR
dc.relation.ispartofabbreviationFood Res. Int.pt_BR
dc.publisher.cityAmsterdampt_BR
dc.publisher.countryHolandapt_BR
dc.publisherElsevier Science Bvpt_BR
dc.date.issued2013pt_BR
dc.date.monthofcirculationAUGpt_BR
dc.identifier.citationFood Research International. Elsevier Science Bv, v. 53, n. 1, n. 417, n. 425, 2013.pt_BR
dc.language.isoenpt_BR
dc.description.volume53pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage417pt_BR
dc.description.lastpage425pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policypt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn0963-9969pt_BR
dc.identifier.wosidWOS:000323239400050pt_BR
dc.identifier.doi10.1016/j.foodres.2013.04.024pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsordocumentnumberFAPESP [2006/53540-9]pt
dc.description.sponsordocumentnumberCAPES [0100102]pt
dc.date.available2014-07-30T13:51:05Z
dc.date.available2015-11-26T17:09:24Z-
dc.date.accessioned2014-07-30T13:51:05Z
dc.date.accessioned2015-11-26T17:09:24Z-
dc.description.provenanceMade available in DSpace on 2014-07-30T13:51:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.description.provenanceMade available in DSpace on 2015-11-26T17:09:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/54968
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/54968-
Appears in Collections:Unicamp - Artigos e Outros Documentos

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