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Type: Artigo de periódico
Title: Analysis of the Antimicrobial Susceptibility of Anaerobic Bacteria Isolated from Endodontic Infections in Brazil during a Period of Nine Years
Author: Gomes, BPFA
Jacinto, RC
Montagner, F
Sousa, ELR
Ferraz, CCR
Abstract: Introduction: The purpose of this study was to analyze the susceptibility of some anaerobic species isolated from a Brazilian population at different periods of time by determining a pattern of development of resistance to frequently prescribed antibiotics in endodontics. Methods: Root canal samples were collected from infected teeth at different periods of time (2000-2002, 2003-2005, and 2007-2008) and microbiologically identified with conventional culture techniques. The susceptibility of Prevotella intermedia/nigrescens, P oralis, Fusobacterium nucleatum, and micra isolated strains was determined by the minimum inhibitory concentration (MIC) of amoxicillin, amoxicillin + clavulanate, benzylpenicillin, clindamycin, erythromycin, and metronidazole by using the E-test method. Results: Amoxicillin and amoxicillin + clavulanate were effective against the majority of species at the different periods of study. Overall, there were low statistical differences regarding the microbial susceptibility between the experimental periods. However, an increase in the anaerobic resistance to penicillin G and clindamycin was observed. Resistance to erythromycin was observed in all species, and there were statistically significant differences between 2000-2002 and 2003-2005 periods for F nucleatum (P<.05) and between 2003-2005 and 2007-2008 periods for P intermedia/nigrescens and P oralis (P<.05). Conclusions: The antimicrobial resistance of anaerobes isolated from primary endodontic infections showed an increase throughout a period of time regarding a specific Brazilian population. (J Endod 2011;37:1058-1062)
Subject: Anaerobic bacteria
antimicrobial agents
Country: EUA
Editor: Elsevier Science Inc
Citation: Journal Of Endodontics. Elsevier Science Inc, v. 37, n. 8, n. 1058, n. 1062, 2011.
Rights: fechado
Identifier DOI: 10.1016/j.joen.2011.05.015
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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