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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleAmygdala enlargement occurs in patients with mesial temporal lobe epilepsy and hippocampal sclerosis with early epilepsy onsetpt_BR
dc.contributor.authorCoan, ACpt_BR
dc.contributor.authorMorita, MEpt_BR
dc.contributor.authorCampos, BMpt_BR
dc.contributor.authorBergo, FPGpt_BR
dc.contributor.authorKubota, BYpt_BR
dc.contributor.authorCendes, Fpt_BR
unicamp.author.emailaccoan@gmail.compt_BR
unicamp.author.emailmarciamorita@gmail.compt_BR
unicamp.author.emailbrunno@fcm.unicamp.brpt_BR
unicamp.author.emailfbergo@gmail.compt_BR
unicamp.author.emailkubota187@gmail.compt_BR
unicamp.author.emailfcendes@unicamp.brpt_BR
unicamp.authorCoan, Ana C. Morita, Marcia E. Campos, Brunno M. Bergo, Felipe P. G. Kubota, Bruno Y. Cendes, Fernando Univ Estadual Campinas, Dept Neurol, Neuroimaging Lab, Campinas, SP, Brazilpt_BR
dc.subjectMesial temporal lobe epilepsypt_BR
dc.subjectAmygdalapt_BR
dc.subjectVolumetrypt_BR
dc.subject.wosSurgerypt_BR
dc.subject.wosAtrophypt_BR
dc.subject.wosFearpt_BR
dc.subject.wosDisorderspt_BR
dc.subject.wosPatternspt_BR
dc.subject.wosFeaturespt_BR
dc.description.abstractMesial temporal lobe epilepsy (MTLE) associated with hippocampal sclerosis (HS) is considered an electroclinical syndrome, and there is a debate whether it is a unique disease or an entity with distinct subtypes. Together with other mesial temporal structures, the amygdala is important in the epileptogenic network of patients with MTLE with HS. During automatic volumetric analysis of mesial structures in a group of 102 patients with MTLE with MRI signs of HS, we observed significant amygdala enlargement in 14 (14%) individuals compared to a group of 79 healthy subjects. The increased amygdala volume was contralateral to the epileptogenic zone and MRI signs of HS in 93% of these patients. Patients with MTLE with HS and enlarged amygdala had significantly earlier epilepsy onset than those without an increase of amygdala volumes. Mesial temporal lobe epilepsy with HS and enlarged amygdala may be a part of the spectrum of this condition. (C) 2013 Elsevier Inc. All rights reserved.pt
dc.relation.ispartofEpilepsy & Behaviorpt_BR
dc.relation.ispartofabbreviationEpilepsy Behav.pt_BR
dc.publisher.citySan Diegopt_BR
dc.publisher.countryEUApt_BR
dc.publisherAcademic Press Inc Elsevier Sciencept_BR
dc.date.issued2013pt_BR
dc.date.monthofcirculationNOVpt_BR
dc.identifier.citationEpilepsy & Behavior. Academic Press Inc Elsevier Science, v. 29, n. 2, n. 390, n. 394, 2013.pt_BR
dc.language.isoenpt_BR
dc.description.volume29pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage390pt_BR
dc.description.lastpage394pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policypt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn1525-5050pt_BR
dc.identifier.wosidWOS:000325422500024pt_BR
dc.identifier.doi10.1016/j.yebeh.2013.08.022pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsordocumentnumberFAPESP [2005/56578-4, 2009/54552-9]pt
dc.date.available2014-07-30T13:48:26Z
dc.date.available2015-11-26T17:57:39Z-
dc.date.accessioned2014-07-30T13:48:26Z
dc.date.accessioned2015-11-26T17:57:39Z-
dc.description.provenanceMade available in DSpace on 2014-07-30T13:48:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.description.provenanceMade available in DSpace on 2015-11-26T17:57:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/54267
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/54267-
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