Please use this identifier to cite or link to this item:
|Type:||Artigo de periódico|
|Title:||Mauritic acid: a new dammarane triterpene from the roots of Mauritia flexuosa L.f. (Arecaceae)|
da Silva, FMA
de Oliveira, AA
de Souza, AQL
de Medeiros, LS
de Souza, ADL
|Abstract:||A new dammarane triterpene named mauritic acid (1) was isolated from the roots of Mauritia flexuosa L.f. The complete structural assignment of this new compound was elucidated from spectroscopic methods. Moreover, this compound was evaluated for its cytotoxicity against human cancer cell lines (OVCAR-8, PCM3, NCIH358M and different leukaemia cell strains). The mauritic acid presented significant cytotoxicity against OVCAR-8, PCM3 and NCIH358M cell lines with IC50 3.02, 2.39 and 6.19M, respectively. The triterpenes 1 and 2 were also tested for their antimicrobial activity against 15 strains of microorganisms, including fungi and bacteria, with the best minimal inhibitory concentration values ranging from 50.8 to 203.5M.|
|Editor:||Taylor & Francis Ltd|
|Citation:||Natural Product Research. Taylor & Francis Ltd, v. 27, n. 22, n. 2118, n. 2125, 2013.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.