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Type: Artigo de periódico
Title: A cross-sectional study of the forearm bone density of long-term users of levonorgestrel-releasing intrauterine system
Author: Bahamondes, L
Espejo-Arce, X
Hidalgo, MM
Hidalgo-Regina, C
Teatin-Juliato, C
Petta, CA
Abstract: BACKGROUND: There are concerns about the effect of hormonal contraceptives on bone mineral density (BMD), but there is currently no information available on the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) on BMD. The objective of this study was to compare the BMD of LNG-IUS users with that of controls using the TCu380A intrauterine device (IUD). MATERIALS AND METHODS: A cross-sectional study paired 53 women, aged 25-51 years, who had been using the LNG-IUS for 7 years, with 53 IUD users, according to age (+/- 1 year) and body mass index (BMI; kg/m(2)) (+/- 1). BMD was evaluated at the midshaft of the ulna and the distal radius of the nondominant forearm using double X-ray absorptiometry. RESULTS: Mean age of women was 34 years. BMI was slightly over 25 in both groups. Estradiol was normal. Mean BMD was 0.469 +/- 0.008 and 0.467 +/- 0.009 and 0.409 +/- 0.009 and 0.411 +/- 0.009 at the midshaft of the ulna and distal radius in LNG-IUS and IUD users, respectively, without significant differences. CONCLUSIONS: Women aged 25-51 years, using the LNG-IUS for 7 years, had a mean BMD similar to that of the control group of TCu380A IUD users.
Subject: bone mineral density
levonorgestrel-releasing intrauterine system
Mirena (R)
Country: Inglaterra
Editor: Oxford Univ Press
Citation: Human Reproduction. Oxford Univ Press, v. 21, n. 5, n. 1316, n. 1319, 2006.
Rights: fechado
Identifier DOI: 10.1093/humrep/dei457
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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