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Type: Artigo de periódico
Title: Major salivary gland damage in allogeneic hematopoietic progenitor cell transplantation assessed by scintigraphic methods
Author: Coracin, F
Correa, MP
Camargo, EE
Peterson, DE
Santos, AD
Vigorito, AC
Oliveira, GB
Eid, KAD
Zulli, R
De Souza, CA
Abstract: Salivary gland dysfunction is a common sequela of hematopoietic progenitor cell transplantation (HPCT). The investigation of major salivary gland dysfunction with sodium pertechnetate scintigraphy is a non-invasive method that provides images of the parotid and submandibular glands. In this prospective trial, 20 HPCT patients were submitted to scintigraphic study with Tc-99m-pertechenate and Ga-67 in order to evaluate the major salivary glands early involvement following HPCT. Major salivary glands were evaluated prior to HCPT as well as at Days +30, +60 and +100 post transplant. Major salivary glands uptake and clearance of Tc-99m-pertechenate results did not demonstrate any functional differences between pre-versus post transplant periods. Results of the Ga-67 scan revealed inflammatory infiltration following HPCT, primarily in submandibular glands, suggest a persistent involvement of major salivary glands up to Day +100 after HPCT.
Subject: major salivary glands
Tc-99m-pertechnetate and gallium-67 scintigraphy
Country: Inglaterra
Editor: Nature Publishing Group
Citation: Bone Marrow Transplantation. Nature Publishing Group, v. 37, n. 10, n. 955, n. 959, 2006.
Rights: fechado
Identifier DOI: 10.1038/sj.bmt.1705351
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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