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Type: Artigo de periódico
Title: Long-term followup of penile carcinoma treated with penectomy and bilateral modified inguinal lymphadenectomy
Author: D'Ancona, CAL
De Lucena, RG
Querne, FAO
Martins, MHT
Denardi, F
Netto, NR
Abstract: Purpose: We evaluated modified inguinal lymphadenectomy in the treatment of penile carcinoma, analyzing the rate of complications compared to complete inguinal lymphadenectomy, the complications in performing lymphadenectomy and penectomy concomitantly, and the long-term locoregional recurrence rate. \ Materials and Methods: A total of 26 patients with squamous cell carcinoma of the penis were clinically assessed, and underwent penectomy and bilateral modified inguinal lymphadenectomy at the same operative time. Frozen section analysis of lymph nodes was performed and if metastases were detected a complete ipsilateral inguinal dissection was performed. Results: A total of 52 modified lymphadenectomies were performed. In 10 procedures lymph node metastasis was present. Clinical staging presented false-positive and false-negative rates of 50% and 7.9%, respectively. The complication rate for modified lymphadenectomy was 38.9% and for complete inguinal lymphadenectomy it was 87.5%. Followup ranged from 5 to 112 months and mean followup of recurrence-free cases was 78 months (range 38 to 112). A total of 18 patients underwent bilateral negative modified inguinal lymphadenectomy and 2 of these experienced locoregional recurrence within 2 years after surgery. Conclusions: Modified inguinal lymphadenectomy causes a lower complication rate than complete inguinal lymphadenectomy. Bilateral modified inguinal lymphadenectomy performed at the same time as penectomy does not increase the complication rate. When frozen section analysis is negative bilaterally, 5.5% of inguinal regions might still harbor occult metastasis. Modified inguinal lymphadenectomy is recommended as a staging procedure in all patients with T2-3 penile carcinoma. A straight followup is required for 2 years since all recurrence was within this period.
Subject: penile neoplasms
lymph node excision
neoplasm metastasis
lymphatic metastasis
Country: EUA
Editor: Lippincott Williams & Wilkins
Citation: Journal Of Urology. Lippincott Williams & Wilkins, v. 172, n. 2, n. 498, n. 501, 2004.
Rights: fechado
Identifier DOI: 10.1097/01.ju.0000132239.28989.e1
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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