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Type: Artigo de periódico
Title: Local side effects observed among long-term users of Norplant contraceptive implants
Author: Alvarez, F
Brache, V
Faundes, A
Jorge, A
Sousa, MH
Abstract: The prevalence of local signs and symptoms related to the site of insertion of implants, and the association of these signs and symptoms with time of use, skin color and body mass index (BMI) was evaluated among users of the Norplant implant system. Three hundred and three Norplant users attending at the reproductive health clinic of PROFAMILIA in Santo Domingo, Dominican Republic, were asked if they had ever had any discomfort at the site/arm of implant insertion and the implant insertion area was examined and hyperpigmentation and hollowing of the surface was recorded. Half of the subjects reported either pain or paresthesia or both, in almost equal numbers, some time since insertion. Hyperpigmentation was observed in 35.6% and hollowing in 22.4% of the subjects. Report of pain and paresthesia was inversely associated to time of use and to BMI. Hyperpigmentation was directly associated to time of use and darker skin, and hollowing of the arm surface in the implants area with time of use and BMI. Local signs and symptoms were more frequent than previously reported, although they were of mild nature and appeared not to worry most of the users. (C) 2003 Elsevier. All rights reserved.
Subject: Norplant implants
local side effects
skin changes
Country: EUA
Editor: Elsevier Science Inc
Citation: Contraception. Elsevier Science Inc, v. 68, n. 2, n. 111, n. 115, 2003.
Rights: fechado
Identifier DOI: 10.1016/S0010-7824(03)00144-6
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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