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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.subject.otherBOMBYX-MORI SILKen
dc.subject.otherBONE REGENERATIONen
dc.typeArtigo de periódicopt_BR
dc.type.categoryoriginal articlept_BR
dc.type.versionpublishedVersionpt_BR
dc.titleA New Method to Prepare Porous Silk Fibroin Membranes Suitable for Tissue Scaffolding Applicationspt_BR
dc.contributor.authorNOGUEIRA, Grinia M.pt_BR
dc.contributor.authorWESKA, Raquel F.pt_BR
dc.contributor.authorVIEIRA JR., Wellington C.pt_BR
dc.contributor.authorPOLAKIEWICZ, Bronislawpt_BR
dc.contributor.authorRODAS, Andrea C. D.pt_BR
dc.contributor.authorHIGA, Olga Z.pt_BR
dc.contributor.authorBEPPU, Marisa M.pt_BR
unicamp.authorNOGUEIRA, Grinia M.:Universidade Estadual de Campinas, Faculdade de Engenharia Químicapt_BR
unicamp.authorWESKA, Raquel F.:Universidade Estadual de Campinas, Faculdade de Engenharia Químicapt_BR
unicamp.authorVIEIRA JR., Wellington C.:Universidade Estadual de Campinas, Faculdade de Engenharpt_BR
unicamp.author.externalRODAS, Andrea C. D.pt
unicamp.author.externalHIGA, Olga Z.pt
unicamp.author.externalPOLAKIEWICZ, Bronislawpt
dc.subjectsilk fibroinpt_BR
dc.subjectporous membranept_BR
dc.subjectbiopolymerpt_BR
dc.subjectbiomaterialpt_BR
dc.subject.wosPolymer Sciencept_BR
dc.description.abstractA new method to prepare porous silk fibroin (SF) membranes without dialysis proposed. Silk fibers were degummed to remove sericin and the resultant fibroin was dissolved in a CaCl(2)-CH(3)CH(2)OH-H(2)O ternary solvent. Rather than undergoing dialysis, a fibroin salty solution was diluted in water and then submitted to a mechanical agitation that led to a phase separation through foam formation on the solution surface. This foam was continually collected and then compacted between plates to remove the excess of water. The membranes presented large pores with diameters of greater than 100 pm (as shown by scanning electron microscopy - SEM), porosity of 68% and water content of 91% w/w. X-ray diffraction (XRD) and infrared spectroscopy (FTIR-ATR) indicated that the membranes present SF in a beta-sheet structure even before the ethanol treatment. A typical elastic deformation profile and degradation under temperature were observed using calorimetric analysis (DSC), thermal gravimetric analysis (TGA) and mechanical tests. As indicated by the in vitro cytotoxicity tests, these membranes present potential for use as scaffolds. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 114: 617-623, 2009en
dc.relation.ispartofJournal of Applied Polymer Sciencept_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherJOHN WILEY & SONS INCpt_BR
dc.date.issued2009pt_BR
dc.identifier.citationJOURNAL OF APPLIED POLYMER SCIENCE, v.114, n.1, p.617-623, 2009pt_BR
dc.language.isoengpt_BR
dc.description.volume114pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage617pt_BR
dc.description.lastpage623pt_BR
dc.rightsfechadopt_BR
dc.rights.holderCopyright JOHN WILEY & SONS INCpt_BR
dc.sourceWOSpt_BR
unicamp.cruespUSPpt_BR
dc.identifier.issn0021-8995pt_BR
dc.identifier.doi10.1002/app.30627pt_BR
dc.identifier.urlhttp://dx.doi.org/10.1002/app.30627pt_BR
dc.identifier.urlhttp://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000268738500073&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecordpt_BR
dc.date.available2013-07-26T17:57:53Z
dc.date.available2016-06-30T19:53:38Z-
dc.date.accessioned2013-07-26T17:57:53Z
dc.date.accessioned2016-06-30T19:53:38Z-
dc.description.provenanceMade available in DSpace on 2013-07-26T17:57:53Z (GMT). No. of bitstreams: 2 art_NOGUEIRA_A_New_Method_to_Prepare_Porous_Silk_2009.pdf.txt: 24958 bytes, checksum: 42a6252b78c780c258bbfc60102853b2 (MD5) art_NOGUEIRA_A_New_Method_to_Prepare_Porous_Silk_2009.pdf: 394068 bytes, checksum: 3ec0e2704e9e08cb8be5c94f513882ee (MD5) Previous issue date: 2009en
dc.description.provenanceMade available in DSpace on 2016-06-30T19:53:38Z (GMT). No. of bitstreams: 2 art_NOGUEIRA_A_New_Method_to_Prepare_Porous_Silk_2009.pdf.txt: 24958 bytes, checksum: 42a6252b78c780c258bbfc60102853b2 (MD5) art_NOGUEIRA_A_New_Method_to_Prepare_Porous_Silk_2009.pdf: 394068 bytes, checksum: 3ec0e2704e9e08cb8be5c94f513882ee (MD5) Previous issue date: 2009en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/487
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/487-
dc.contributor.unidadeFEQpt
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