Please use this identifier to cite or link to this item:
|Title:||Chemical composition and cytotoxic activity of the essential oils of Cantinoa stricta (Benth.) Harley & J.F.B. Pastore (Lamiaceae)|
|Author:||Scharf, Dilamara Riva|
Simionatto, Edésio L.
Carvalho, João E.
Salvador, Marcos J.
Santos, Élide P.
Stefanello, Maria Élida A.
|Abstract:||The essential oils from the leaves and flowers of Cantinoa stricta (Benth.) Harley & J.F.B. Pastore (Lamiaceae) were obtained by hydrodistillation and analyzed by GC/FID and GC/ MS. The major components of both oils were caryophyllene oxide (leaf – 31.6%; flower – 21.7%) and cis-pinane (leaf – 15.4%; flower – 9.7%). The flower oil also contained significant amounts of a -pinene (9.4%) and b -pinene (9.1%). The oils were tested in vitro against U251 (glioma), UACC-62 (melanoma), MCF-7 (breast), NCI-H460 (lung), PC-3 (prostate), K-562 (leukemia) human cancer cell lines and against HaCat (no cancer cell), using the sulforhodamine B method. Both oils showed antiproliferative activity against all tested cells lines (TGI < 50 m g/mL), with exception of K562 cells. The highest activity was observed against MCF-7 cell lines (TGI = 4.54-10.36 m g/mL).|
Essências e óleos essenciais
|Editor:||A C G Publications|
|Appears in Collections:||IB - Artigos e Outros Documentos|
CPQBA - Artigos e Outros Documentos
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.