Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/356602
Type: Outro documento
Title: Chemical composition and cytotoxic activity of the essential oils of Cantinoa stricta (Benth.) Harley & J.F.B. Pastore (Lamiaceae)
Author: Scharf, Dilamara Riva
Simionatto, Edésio L.
Carvalho, João E.
Salvador, Marcos J.
Santos, Élide P.
Stefanello, Maria Élida A.
Abstract: The essential oils from the leaves and flowers of Cantinoa stricta (Benth.) Harley & J.F.B. Pastore (Lamiaceae) were obtained by hydrodistillation and analyzed by GC/FID and GC/ MS. The major components of both oils were caryophyllene oxide (leaf – 31.6%; flower – 21.7%) and cis-pinane (leaf – 15.4%; flower – 9.7%). The flower oil also contained significant amounts of a -pinene (9.4%) and b -pinene (9.1%). The oils were tested in vitro against U251 (glioma), UACC-62 (melanoma), MCF-7 (breast), NCI-H460 (lung), PC-3 (prostate), K-562 (leukemia) human cancer cell lines and against HaCat (no cancer cell), using the sulforhodamine B method. Both oils showed antiproliferative activity against all tested cells lines (TGI < 50 m g/mL), with exception of K562 cells. The highest activity was observed against MCF-7 cell lines (TGI = 4.54-10.36 m g/mL).
Subject: Atividade citotóxica
Essências e óleos essenciais
Country: Turquia
Editor: A C G Publications
Rights: Fechado
Address: http://www.acgpubs.org/article/records-of-natural-products/2016/2-march-april/chemical-composition-and-cytotoxic-activity-of-the-essential-oils-of-cantinoa-stricta-benth-harley-jfb-pastore-lamiaceae
Date Issue: 2016
Appears in Collections:IB - Artigos e Outros Documentos
CPQBA - Artigos e Outros Documentos

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