Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/348011
Type: Artigo
Title: Epidemiology and predictors of a poor outcome in elderly patients with candidemia
Author: Guimaraes, Thais
Nucci, Marcio
Mendonca, Joao S.
Martinez, Roberto
Brito, Ligia R.
Silva, Nivia
Moretti, Maria Luiza
Salomao, Reinaldo
Colombo, Arnaldo L.
Abstract: Candidemia affects patient populations from neonates to the elderly. Despite this, little information is available about the epidemiology of candidemia in elderly patients. We performed a retrospective analysis of 987 episodes of candidemia in adults (>14 years of age) from the databases of three laboratory-based surveys of candidemia performed at 14 tertiary care hospitals. Patients aged >= 60 years were considered elderly (group 1, n = 455, 46%) and were compared to younger patients (group 2, n = 532, 54%) regarding demographics, underlying diseases, comorbidities, exposure to medical procedures, species, treatment, and outcome. The median APACHE II score was significantly higher in the elderly patients (19 vs. 15, p = 0.03). Variables that were observed significantly more frequently in elderly patients included admission to an intensive care unit, diabetes mellitus, renal failure, cardiac disease, lung disease, receipt of antibiotics or H2 blockers, insertion of a central venous catheter, mechanical ventilation, and candidemia due to. The median APACHE II score was significantly higher in the elderly patients (19 vs. 15, p = 0.03). Variables that were observed significantly more frequently in elderly patients included admission to an intensive care unit, diabetes mellitus, renal failure, cardiac disease, lung disease, receipt of antibiotics or H2 blockers, insertion of a central venous catheter, mechanical ventilation, and candidemia due to. Elderly patients account for a substantial proportion of patients with candidemia and have a higher mortality compared to younger patients. (C) 2012 International Society for Infectious Diseases
Subject: Candidemia
Circulação sanguínea
Country: Reino Unido
Editor: Elsevier
Rights: Aberto
Identifier DOI: 10.1016/j.ijid.2012.02.005
Address: https://www.sciencedirect.com/science/article/pii/S120197121200063X
Date Issue: 2012
Appears in Collections:FCM - Artigos e Outros Documentos

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