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Type: Artigo
Title: Cost-utility analysis of outpatient parenteral antimicrobial therapy (OPAT) in the brazilian national health system
Author: Psaltikidis, Eliane Molina
Silva, Everton Nunes da
Moretti, Maria Luiza
Trabasso, Plinio
Stucchi, Raquel Silveira Bello
Aoki, Francisco Hideo
Cardoso, Luis Gustavo de Oliveira
Hofling, Christian Cruz
Bachur, Luis Felipe
Ponchet, Danilo da Fontoura
Colombrini, Maria Rosa Ceccato
Tozzi, Cintia Soarez
Ramos, Rosana Fins
Costa, Sandra Mara Queiroz
Resende, Mariangela Ribeiro
Abstract: Outpatient parenteral antimicrobial therapy (OPAT) has been used for decades in different countries to reduce hospitalization rates, with favorable clinical and economic outcomes. This study assesses the cost-utility of OPAT compared to inpatient parenteral antimicrobial therapy (IPAT) from the perspective of a public university hospital and the Brazilian National Health System (Unified Health System -SUS). Methods: Prospective study with adult patients undergoing OPAT at an infusion center, compared to IPAT. Clinical outcomes and quality-adjusted life year (QALY) were assessed, as well as a micro-costing. Cost-utility analysis from the hospital and SUS perspectives were conducted by means of a decision tree, within a 30-day horizon time. Results: Forty cases of OPAT (1112 days) were included and monitored, with a favorable outcome in 97.50%. OPAT compared to IPAT generated overall savings of 31.86% from the hospital perspective and 26.53% from the SUS perspective. The intervention reduced costs, with an incremental cost-utility ratio of -44,395.68/QALY for the hospital and -48,466.70/QALY for the SUS, with better cost-utility for treatment times greater than 14 days. Sensitivity analysis confirmed the stability of the model. Conclusion: Our economic assessment demonstrated that, in the Brazilian context, OPAT is a cost-saving strategy both for hospitals and for the SUS
Subject: Avaliação econômica
Country: Reino Unido
Editor: Taylor & Francis
Rights: Fechado
Identifier DOI: 10.1080/14737167.2019.1541404
Date Issue: 2019
Appears in Collections:FCM - Artigos e Outros Documentos
HC - Artigos e Outros Documentos

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