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|Title:||Flaxleaf fleabane leaves (conyza bonariensis), a new functional nonconventional edible plant?|
|Author:||Schechtel, Suzane Lucas|
Matos, Vanessa Cristina Rodrigues de
Santos, Jânio Sousa
Cruz, Thiago Mendanha
Marques, Mariza Boscacci
Furtado, Marianna Miranda
Sant'Ana, Anderson S.
Carmo, Mariana Araújo Vieira do
Ribeiro, Jéssica Caroline Bigaski
|Abstract:||This work aimed to investigate the phytochemical composition, nutritional value, antioxidant, antihemolytic, antihyperglycemic, and antiproliferative activities of flaxleaf fleabane (Conyza bonariensis) leaves. Different concentrations of water and ethanol (0:100, 25:75, 50:50, 75:25, and 100:0 v/v) were used in the extraction process and results showed that the hydroalcoholic extract (50:50 v/v) presented the highest total phenolics, ortho‐diphenolics, Folin‐Ciocalteu reducing capacity, FRAP, and Fe2+ chelating ability values. Flaxleaf fleabane leaves (FFL) contained 19.6 g/100 g of fibers and 26 g/100 g of proteins. Ellagic acid, procyanidin A2, caffeic, rosmarinic, gallic, and 2,5‐dihydroxybenzoic acids were the main phenolics. This phenolic‐rich extract inhibited the lipid oxidation of Wistar rat brain (IC50 = 863.0 mg GAE/L), inhibited α‐glucosidase activity (IC50 = 435.4 µg/mL), protected human erythrocytes against mechanical hemolysis at different osmolarity conditions, and showed cytotoxic/antiproliferative effects against human ileocecal adenocarcinoma cells (HCT8; IC50 = 552.6 µg/mL) but no cytotoxicity toward noncancerous human lung fibroblast (IMR90). Overall, FFL showed potential to be explored by food companies to be a source of proteins, natural color substances, and phenolic compounds|
|Appears in Collections:||FEA - Artigos e Outros Documentos|
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