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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampMarson, Fernando Augusto de Lima-
dc.typeArtigopt_BR
dc.titleLactulose breath testing can be a positive predictor before weight gain in participants with obesity submitted to roux-en-y gastric bypasspt_BR
dc.contributor.authorCoelho, Luciano Kowalski-
dc.contributor.authorCarvalho, Nayara Salgado-
dc.contributor.authorNavarro-Rodriguez, Tomas-
dc.contributor.authorMarson, Fernando Augusto Lima-
dc.contributor.authorCarvalho, Paulo Jose Pereira Campos-
dc.subjectCrescimento bacterianopt_BR
dc.subjectCirurgia bariátricapt_BR
dc.subjectObesidadept_BR
dc.subject.otherlanguageBacterial growthpt_BR
dc.subject.otherlanguageBariatric surgerypt_BR
dc.subject.otherlanguageObesitypt_BR
dc.description.abstractSmall intestinal bacterial overgrowth (SIBO) is defined as the colonization of fermentative bacteria in the duodenum and jejunum. The alteration of digestive anatomy promoted by bariatric surgery may be a pre-disposing factor for SIBO. In this context, the prevalence of SIBO in participants undergoing bariatric surgery using Roux-en-Y gastric bypass (BGYR) was evaluated.Participants, both sexes, older than 18 years, were those who (a) had bariatric surgery by the BGYR technique at least 1 year before the data collection and (b) did not use antibiotics recently. The SIBO diagnosis was established through the hydrogen breath test (H2BT), with intake of lactulose and serial collection of breath samples over 2 h. A test with ≥ 12-point elevation over the basal sample at 60 min after substrate intake was deemed positive.A total of 18 participants (14 females (77.8%)) were enrolled with a mean age of 50.5 years (range, 23 to 79 years). The interval between surgery and data collection ranged from 5 to 20 years (mean, 11.2 years). The mean preoperative body mass index (BMI) was 44.6 kg/m2 (range, 36.7–56.2 kg/m2). The H2RT with lactulose was positive for SIBO in seven (six female) participants. The participants with negative test measured trough H2BT with lactulose had a lower mean BMI of 28.69 kg/m2, in comparison with the positive group, which presented a mean BMI of 33.04 kg/m2 (p value = 0.041).Our data point to a high prevalence of SIBO (38.8%) in patients undergoing BGYR with a value in accordance with the literature. Moreover, the differences in BMI between negative and positive groups by H2BT with lactulose evidenced a weight gain relapse in participants with SIBOpt_BR
dc.relation.ispartofObesity Surgerypt_BR
dc.relation.ispartofabbreviationObes. surg.pt_BR
dc.publisher.cityNew York, NYpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherSpringerpt_BR
dc.date.issued2019-11-
dc.date.monthofcirculationNov.pt_BR
dc.language.isoengpt_BR
dc.description.volume29pt_BR
dc.description.issuenumber11pt_BR
dc.description.firstpage3457pt_BR
dc.description.lastpage3464pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0960-8923pt_BR
dc.identifier.eissn1708-0428pt_BR
dc.identifier.doi10.1007/s11695-019-04006-zpt_BR
dc.identifier.urlhttps://link.springer.com/article/10.1007/s11695-019-04006-zpt_BR
dc.date.available2020-03-18T17:37:09Z-
dc.date.accessioned2020-03-18T17:37:09Z-
dc.description.provenanceSubmitted by Susilene Barbosa da Silva (susilene@unicamp.br) on 2020-03-18T17:37:09Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-07-20T14:19:50Z : No. of bitstreams: 1 000495797200006.pdf: 500855 bytes, checksum: 89a43f3ca0254d5e27c88be75f9b64dc (MD5)en
dc.description.provenanceMade available in DSpace on 2020-03-18T17:37:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/336815-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordBreath testpt_BR
dc.subject.keywordLactulosept_BR
dc.subject.keywordSmall intestinept_BR
dc.identifier.source000495797200006pt_BR
dc.creator.orcid0000-0003-4955-4234pt_BR
dc.type.formArtigo originalpt_BR
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