In vitro antimicrobial activity of calcium hydroxide pastes and their vehicles against selected microorganisms

Gomes, Brenda Paula Figueiredo de Almeida; Ferraz, Caio Cezar Randi; Vianna, Morgana Eli; Rosalen, Pedro Luiz; Zaia, Alexandre Augusto; Teixeira, Fabricio Batista; Souza-Filho, Francisco José de

Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/33658

Type:	Artigo
Title:	In vitro antimicrobial activity of calcium hydroxide pastes and their vehicles against selected microorganisms
Title Alternative:	Atividade antimicrobiana in vitro das pastas de hidróxido de cálcio e seus veículos sobre microrganismos específicos
Author:	Gomes, Brenda Paula Figueiredo de Almeida Ferraz, Caio Cezar Randi Vianna, Morgana Eli Rosalen, Pedro Luiz Zaia, Alexandre Augusto Teixeira, Fabricio Batista Souza-Filho, Francisco José de
Abstract:	The aim of this study was to investigate in vitro the antimicrobial activity of calcium hydroxide in combination with several vehicles against some microorganisms commonly isolated from root canals. Antimicrobial activity was determined by the agar diffusion method. Stainless-steel cylinders were placed on each inoculated agar medium. The test medicaments and their controls were placed inside the cylinders. The zones of growth inhibition were measured and recorded after incubation for each plate and the results were analyzed statistically (ANOVA). The in vitro antimicrobial effects of the medications were ranked from strongest to weakest as follows: Ca(OH)2 + CMCP + glycerine, Ca(OH)2 + CMCP, Ca(OH)2 + glycerine, Ca(OH)2 + anesthetic, Ca(OH)2 + saline, Ca(OH)2 + H2O, Ca(OH)2 + polyethyleneglycol. The pastes with oily vehicles showed significantly larger mean zones of inhibition compared to those with aqueous or viscous vehicles. It was concluded that diffusion and antimicrobial activity of calcium hydroxide were affected by the type of vehicle used. The aim of this study was to investigate in vitro the antimicrobial activity of calcium hydroxide in combination with several vehicles against some microorganisms commonly isolated from root canals. Antimicrobial activity was determined by the agar diffusion method. Stainless-steel cylinders were placed on each inoculated agar medium. The test medicaments and their controls were placed inside the cylinders. The zones of growth inhibition were measured and recorded after incubation for each plate and the results were analyzed statistically (ANOVA). The in vitro antimicrobial effects of the medications were ranked from strongest to weakest as follows: Ca(OH)2 + CMCP + glycerine, Ca(OH)2 + CMCP, Ca(OH)2 + glycerine, Ca(OH)2 + anesthetic, Ca(OH)2 + saline, Ca(OH)2 + H2O, Ca(OH)2 + polyethyleneglycol. The pastes with oily vehicles showed significantly larger mean zones of inhibition compared to those with aqueous or viscous vehicles. It was concluded that diffusion and antimicrobial activity of calcium hydroxide were affected by the type of vehicle used
metadata.dc.description.abstractalternative:	O objetivo deste trabalho foi investigar in vitro a atividade antimicrobiana do hidróxido de cálcio em combinação com vários veículos contra alguns microrganismos mais frequentemente isolados dos canais radiculares. A atividade antimicrobiana foi determinada pelo método de difusão no ágar. Cilindros de aço inoxidável foram colocados sobre as placas de agar já inoculadas, dentro dos quais os medicamentos testados e seus controles foram introduzidos. As zonas de inibição do crescimento microbiano foram medidas e anotadas após o período de incubação de cada placa e os resultados foram analisados estatisticamente. A atividade antimicrobiana in vitro dos medicamentos testados, em ordem decrescente, foi: Ca(OH)2 + PMCF + glicerina, Ca(OH)2 + PMCF, Ca(OH)2 + glicerina, Ca(OH)2 + anestésico, Ca(OH)2 + salina, Ca(OH)2 + H2O, Ca(OH)2 + polietilenoglicol. Pastas com veículos oleosos produziram as maiores zonas de inibição, quando comparadas com as com veículos aquosos ou oleosos. Concluimos que a habilidade de difusão e a atividade antimicrobiana do hidróxido de cálcio estão relacionadas com os tipos de veículos utilizados
Subject:	Microrganismos
Country:	Brasil
Editor:	Fundação Odontológica de Ribeirão Preto
Citation:	Brazilian Dental Journal. Fundação Odontológica de Ribeirão Preto, v. 13, n. 3, p. 155-161, 2002.
Rights:	aberto
Identifier DOI:	10.1590/S0103-64402002000300002
Address:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402002000300002
Date Issue:	2002
Appears in Collections:	FOP - Artigos e Outros Documentos

Files in This Item:

File	Description	Size	Format
S0103-64402002000300002.pdf		51.57 kB	Adobe PDF	View/Open

Show full item record Recommend this item