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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeResenhapt_BR
dc.titleAntimicrobials: A Global Alliance For Optimizing Their Rational Use In Intra-abdominal Infections (agora)pt_BR
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dc.contributor.authorPpt_BR
unicamp.author.emailmassimosartelli@gmail.compt_BR
dc.subjectIntensive-care-unitpt_BR
dc.subjectSpectrum-beta-lactamasept_BR
dc.subjectCritically-ill Patientspt_BR
dc.subjectGram-negative Bacteriapt_BR
dc.subjectVancomycin-resistant Enterococcipt_BR
dc.subjectClostridium-difficile Infectionpt_BR
dc.subjectVentilator-associated Pneumoniapt_BR
dc.subjectBlood-stream Infectionspt_BR
dc.subjectCarbapenemase-producing Enterobacteriaceaept_BR
dc.subjectClinical-practice Guidelinespt_BR
dc.description.abstractIntra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.en
dc.relation.ispartofWorld Journal of Emergency Surgerypt_BR
dc.publisher.cityLONDONpt_BR
dc.publisherBIOMED CENTRAL LTDpt_BR
dc.date.issued2016pt_BR
dc.identifier.citationWorld Journal Of Emergency Surgery. BIOMED CENTRAL LTD, n. 11, n. 33, p. .pt_BR
dc.language.isoEnglishpt_BR
dc.description.volume11pt_BR
dc.description.issuenumberpt_BR
dc.description.lastpagept_BR
dc.rightsabertopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1749-7922pt_BR
dc.identifier.wosidWOS:000379727600001pt_BR
dc.identifier.doi10.1186/s13017-016-0089-ypt_BR
dc.identifier.urlhttp://wjes.biomedcentral.com.ez88.periodicos.capes.gov.br/articles/10.1186/s13017-016-0089-ypt_BR
dc.date.available2016-12-06T18:32:02Z-
dc.date.accessioned2016-12-06T18:32:02Z-
dc.description.provenanceMade available in DSpace on 2016-12-06T18:32:02Z (GMT). No. of bitstreams: 1 000379727600001.pdf: 881915 bytes, checksum: 58ad9fbb79645181d9b9d9d74b450f4c (MD5) Previous issue date: 2016en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/320431-
dc.description.conferencelocationpt_BR
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