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Type: Resenha
Title: Antimicrobials: A Global Alliance For Optimizing Their Rational Use In Intra-abdominal Infections (agora)
Author: Sartelli
M; Weber
DG; Ruppe
E; Bassetti
M; Wright
BJ; Ansaloni
L; Catena
F; Coccolini
F; Abu-Zidan
FM; Coimbra
R; Moore
EE; Moore
FA; Maier
RV; De Waele
JJ; Kirkpatrick
AW; Griffiths
EA; Eckmann
C; Brink
AJ; Mazuski
JE; May
AK; Sawyer
RG; Mertz
D; Montravers
P; Kumar
A; Roberts
JA; Vincent
JL; Watkins
RR; Lowman
W; Spellberg
B; Abbott
IJ; Adesunkanmi
AK; Al-Dahir
S; Al-Hasan
MN; Agresta
F; Althani
AA; Ansari
S; Ansumana
R; Augustin
G; Bala
M; Balogh
ZJ; Baraket
O; Bhangu
A; Beltran
MA; Bernhard
M; Biffl
WL; Boermeester
MA; Brecher
SM; Cherry-Bukowiec
JR; Buyne
OR; Cainzos
MA; Cairns
KA; Camacho-Ortiz
A; Chandy
SJ; Jusoh
AC; Chichom-Mefire
A; Colijn
C; Corcione
F; Cui
YF; Curcio
D; Delibegovic
S; Demetrashvili
Z; De Simone
B; Dhingra
S; Diaz
JJ; Di Carlo
I; Dillip
A; Di Saverio
S; Doyle
MP; Dorj
G; Dogjani
A; Dupont
H; Eachempati
SR; Enani
MA; Egiev
VN; Elmangory
MM; Ferrada
P; Fitchett
JR; Fraga
GP; Guessennd
N; Giamarellou
H; Ghnnam
W; Gkiokas
G; Goldberg
SR; Gomes
CA; Gomi
H; Guzman-Blanco
M; Haque
M; Hansen
S; Hecker
A; Heizmann
WR; Herzog
T; Hodonou
AM; Hong
SK; Kafka-Ritsch
R; Kaplan
LJ; Kapoor
G; Karamarkovic
A; Kees
MG; Kenig
J; Kiguba
R; Kim
PK; Kluger
Y; Khokha
V; Koike
K; Kok
KYY; Kong
V; Knox
MC; Inaba
K; Isik
A; Iskandar
K; Ivatury
RR; Labbate
M; Labricciosa
FM; Laterre
PF; Latifi
R; Lee
JG; Lee
YR; Leone
M; Leppaniemi
A; Li
YS; Liang
SY; Loho
T; Maegele
M; Malama
S; Marei
HE; Martin-Loeches
I; Marwah
S; Massele
A; McFarlane
M; Melo
RB; Negoi
I; Nicolau
DP; Nord
CE; Ofori-Asenso
R; Omari
AH; Ordonez
CA; Ouadii
M; Pereira
GA; Piazza
D; Pupelis
G; Rawson
TM; Rems
M; Rizoli
S; Rocha
C; Sakakhushev
B; Sanchez-Garcia
M; Sato
N; Lohse
HAS; Sganga
G; Siribumrungwong
B; Shelat
VG; Soreide
K; Soto
R; Talving
P; Tilsed
JV; Timsit
JF; Trueba
G; Trung
NT; Ulrych
J; van Goor
H; Vereczkei
A; Vohra
RS; Wani
I; Uhl
W; Xiao
YH; Yuan
KC; Zachariah
SK; Zahar
JR; Zakrison
TL; Corcione
A; Melotti
RM; Viscoli
C; Viale
Abstract: Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Subject: Intensive-care-unit
Critically-ill Patients
Gram-negative Bacteria
Vancomycin-resistant Enterococci
Clostridium-difficile Infection
Ventilator-associated Pneumonia
Blood-stream Infections
Carbapenemase-producing Enterobacteriaceae
Clinical-practice Guidelines
Citation: World Journal Of Emergency Surgery. BIOMED CENTRAL LTD, n. 11, n. 33, p. .
Rights: aberto
Identifier DOI: 10.1186/s13017-016-0089-y
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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