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Type: research-article
Title: Impact of micronutrients supplementation on bone repair around implants: microCT and counter-torque analysis in rats
Author: Pimentel
Suzana Peres; Casarin
Renato Correa; Ribeiro
Fernanda Vieira; Cirano
Fabiano Ribeiro; Rovaris
Karla; Haiter Neto
Francisco; Casati
Marcio Zaffalon
Abstract: The use of natural substances and micronutritional approaches has been suggested as a therapeutic alternative to benefit the bone healing associated with no side effects. Nevertheless, the influence of micronutritional interventions with therapeutic proprieties on the bone repair has yet to be intensely evaluated, and no evidence is available exploring the impact of micronutrient supplementation on the peri-implant bone healing. Objective This study investigated the effect of micronutrients supplementation on the bone repair around implants. Material and Methods One screw-shaped titanium implant was inserted in each tibia of each rat, which were assigned to: daily administration, for 30 d, of the placebo solution (Placebo group-n:18) or micronutrients supplementation (Micronutrients group-n:18), based on calcium, magnesium, zinc, and vitamin D3 intake. After, the animals were sacrificed. One of the implants was removed by applying a counter-torque force to evaluate the force to rupture the bone-implant interface. The other implant was evaluated by microcomputed tomography (CT) examination to determine the bone-to-implant contact (BIC) and the bone volume (BV/TV). Results No statistically significant differences were observed between the groups for both counter-torque values and microCT parameters (p>0.05). Conclusion Within the limits of this study, micronutrients supplementation did not provide additional benefits to the bone healing around dental implants.
Citation: Journal Of Applied Oral Science, 24, 1, p.45-. 2016.
Rights: aberto
Identifier DOI: 10.1590/1678-775720150293
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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