Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/243961
Type: Artigo de periódico
Title: A Field Guide To Current Advances In Paediatric Movement Disorders
Author: Silveira-Moriyama
Laura; Lin
Jean-Pierre
Abstract: Purpose of review Recent advances in neurogenetics, neuroimmunology and nonpharmacological treatments have reshaped the field of paediatric movement disorders. In this review, we put recent findings into context providing a framework to enable navigation of the expanding literature in this field. Recent findings Anti-NMDA receptor encephalitis has proven to be a significant cause of treatable movement disorder in children and to present a multifaceted link with herpes simplex encephalitis. The growing use of next-generation sequencing in both research and clinical practice has unravelled an expanding number of genes related to paediatric movement disorders as well as expanding spectrums of variable expressivity and phenotypic pleiotropy for various genes. Behavioural therapies have been proven efficacious in Tourette's syndrome and are likely to be helpful in complex motor stereotypies. Management of dystonia remains a clinical priority and challenge. The rapid advance of translational medicine has had major impacts on the field of paediatric movement disorders including diagnosis and treatment of these conditions. Video abstract [GRAPHICS]
Subject: D-aspartate Receptor
Deep Brain-stimulation
Aicardi-goutieres Syndrome
Genotype-phenotype Correlation
Pla2g6-associated Neurodegeneration Plan
Herpes-simplex Encephalitis
Bilateral Striatal Necrosis
Complex Motor Stereotypies
Dystonic Cerebral-palsy
Prrt2 Gene-mutations
Country: PHILADELPHIA
Editor: LIPPINCOTT WILLIAMS & WILKINS
Citation: A Field Guide To Current Advances In Paediatric Movement Disorders. Lippincott Williams & Wilkins, v. 28, p. 437-446 AUG-2015.
Rights: fechado
Identifier DOI: 10.1097/WCO.0000000000000214
Address: http://www.ncbi.nlm.nih.gov/pubmed/26110804
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
wos_000360905000019.pdf391.96 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.