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Type: Artigo de periódico
Title: A pituitary adenoma secreting follicle-stimulating hormone with ovarian hyperstimulation: treatment using a gonadotropin-releasing hormone antagonist
Author: Garmes, Heraldo Mendes
Grassiotto, Oswaldo Rocha
Fernandes, Yvens Barbosa
Queiroz, Luciano de Souza
Vassalo, Jose
de Oliveira, Daniel Minutti
Benetti-Pinto, Cristina Laguna
Abstract: Objective: To describe the management of a patient with a pituitary adenoma secreting follicle-stimulating hormone (FSH) associated with ovarian hyperstimulation who was treated with a gonadotropin-releasing hormone (GnRH) antagonist. Design: Case report. Setting: University teaching hospital. Patient(s): A woman of reproductive age with secondary amenorrhea and ovarian hyperstimulation due to a pituitary adenoma secreting FSH, which persisted after transsphenoidal surgery. Intervention(s): Clinical treatment with a GnRH antagonist. Main Outcome Measure(s): A decrease in serum estradiol levels. Result(s): During the treatment period, ovarian hyperstimulation decreased as shown by a reduction in estradiol levels and an improvement in the patient's clinical condition and in the ultrasonography parameters. Conclusion(s): The GnRH antagonist was found to be effective for the short-term treatment of ovarian hyperstimulation secondary to a pituitary adenoma secreting FSH, thus representing a therapeutic option that should be taken into consideration in such cases. (Fertil Steril (R) 2012;97:231-4. (C) 2012 by American Society for Reproductive Medicine.)
Subject: FSH-secreting pituitary tumor
GnRH antagonist
pituitary adenoma
ovarian hyperstimulation syndrome
Editor: Elsevier
Citation: Fertility and Sterility. Elsevier, v.97, n.1, p.231-234, 2012
Rights: fechado
Identifier DOI: 10.1016/j.fertnstert.2011.10.015
Date Issue: 2012
Appears in Collections:FCM - Artigos e Outros Documentos

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