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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleAnimal Model For Training In Sentinel Lymph Node Biopsy Of The Stomach Through Combined Methods.pt_BR
dc.contributor.authorAlves, José Robertopt_BR
dc.contributor.authorLopes, Luiz Robertopt_BR
dc.contributor.authorMeirelles, Luciana Rodrigues dept_BR
dc.contributor.authorRamos, Celso Daríopt_BR
dc.contributor.authorSasasaki, Tâniapt_BR
dc.contributor.authorAndreollo, Nelson Adamipt_BR
unicamp.authorJosé Roberto Alves, UNICAMP, Campinas, SP, Brazil. joserobertoalves1980@gmail.compt_BR
unicamp.author.externalLuiz Roberto Lopes,pt
unicamp.author.externalLuciana Rodrigues de Meirelles,pt
unicamp.author.externalCelso Darío Ramos,pt
unicamp.author.externalTânia Sasasaki,pt
unicamp.author.externalNelson Adami Andreollo,pt
dc.subjectAnimalspt_BR
dc.subjectBiopsy, Needlept_BR
dc.subjectDisease Models, Animalpt_BR
dc.subjectLymph Nodespt_BR
dc.subjectMalept_BR
dc.subjectRabbitspt_BR
dc.subjectSentinel Lymph Node Biopsypt_BR
dc.subjectStomachpt_BR
dc.subjectTechnetiumpt_BR
dc.description.abstractCreate and validate a proposed animal model for training in sentinel lymph node biopsy of the stomach. In thirty-two rabbits, through a laparotomy, they received a subserosal injection of 0.1 ml of phytate labeled with technetium-99m (0.2 mCi) in the anterior wall of the gastric corpus, followed by 0.2 ml of Blue Patent V(®) 2.5%, through the same puncture site. Suspicious lymph nodes were searched in vivo at five, ten and 20 minutes, both visually (Blue Patent stained lymph nodes) and with a manual gamma radiation detector (to detect suspected radioactive lymph nodes). After 20 minutes, was performed resection of these for further evaluation of radioactivity (ex vivo) and histological study. Lymph nodes were identified in 30 rabbits (Average of 2.2 lymph nodes per animal). Of the 90 suspected lymph nodes that occurred in the study, 70 cases (77.8%) were histologically confirmed for lymphoid tissue. Of these, the majority were located in the periesophageal region of the gastric fundus. The sample presented a mortality rate of 6.25% and nine complications related to the method, which interfered in the identification of the lymph nodes. The animal model for sentinel node biopsy in rabbit stomachs proved to be feasible, with low complexity and reproduced the difficulties encountered for gastric lymph node biopsy in humans, being adequate for surgical training.en
dc.relation.ispartofActa Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgiapt_BR
dc.relation.ispartofabbreviationActa Cir Braspt_BR
dc.date.issued2012-Decpt_BR
dc.identifier.citationActa Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia. v. 27, n. 12, p. 833-40, 2012-Dec.pt_BR
dc.language.isoengpt_BR
dc.description.volume27pt_BR
dc.description.firstpage833-40pt_BR
dc.rightsabertopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1678-2674pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/23207748pt_BR
dc.date.available2015-11-27T13:29:04Z-
dc.date.accessioned2015-11-27T13:29:04Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:29:04Z (GMT). No. of bitstreams: 1 pmed_23207748.pdf: 815489 bytes, checksum: 64c324ea89d408df1ebaa4846c7bb8d7 (MD5) Previous issue date: 2012en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/200285-
dc.identifier.idPubmed23207748pt_BR
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