Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/199833
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleEffects Of Eccentric Exercise On Systemic Concentrations Of Pro- And Anti-inflammatory Cytokines And Prostaglandin (e2): Comparison Between Young And Postmenopausal Women.pt_BR
dc.contributor.authorConceição, Miguel Soarespt_BR
dc.contributor.authorLibardi, Cleiton Augustopt_BR
dc.contributor.authorNogueira, Felipe Romano Damaspt_BR
dc.contributor.authorBonganha, Valériapt_BR
dc.contributor.authorGáspari, Arthur Fernandespt_BR
dc.contributor.authorChacon-Mikahil, Mara Patrícia Trainapt_BR
dc.contributor.authorCavaglieri, Cláudia Reginapt_BR
dc.contributor.authorMadruga, Vera Aparecidapt_BR
unicamp.authorMiguel Soares Conceição, Laboratory of Exercise Physiology, (FISEX), Faculty of Physical Education (FEF), State University of Campinas (UNICAMP), Campinas, Brazil. conceicao.miguel0106@gmail.compt_BR
unicamp.author.externalCleiton Augusto Libardi,pt
unicamp.author.externalFelipe Romano Damas Nogueira,pt
unicamp.author.externalValéria Bonganha,pt
unicamp.author.externalArthur Fernandes Gáspari,pt
unicamp.author.externalMara Patrícia Traina Chacon-Mikahil,pt
unicamp.author.externalCláudia Regina Cavaglieri,pt
unicamp.author.externalVera Aparecida Madruga,pt
dc.subjectAdultpt_BR
dc.subjectAge Factorspt_BR
dc.subjectAnti-inflammatory Agentspt_BR
dc.subjectArmpt_BR
dc.subjectCytokinespt_BR
dc.subjectDinoprostonept_BR
dc.subjectExercisept_BR
dc.subjectFemalept_BR
dc.subjectHumanspt_BR
dc.subjectInflammation Mediatorspt_BR
dc.subjectMiddle Agedpt_BR
dc.subjectMuscle Contractionpt_BR
dc.subjectPostmenopausept_BR
dc.subjectRange Of Motion, Articularpt_BR
dc.subjectYoung Adultpt_BR
dc.description.abstractThe present study aimed to analyze the magnitude of muscle damage and inflammatory responses induced by eccentric exercise in young (YW) and postmenopausal women (PMW). Seventeen healthy women (nine YW, 23.89 ± 2.03 years; and eight PMW, 51.13 ± 5.08 years) performed five sets of six maximal eccentric actions of the elbow flexors. Changes in isometric strength, range of motion, muscle soreness, and upper-arm circumference were evaluated pre, post, 24, 48, and 72 h following eccentric exercise. Changes in creatine kinase activity, interleukin 6 (IL-6), interleukin 10 (IL-10), tumor necrosis factor-α (TNF-α), and prostaglandin E(2) (PGE(2)) were measured pre, 24, 48, and 72 h following eccentric exercise. For intra and inter-group analysis, a two-way repeated measures ANOVA was applied followed by a Tukey's post hoc test. Pearson's correlation was used to analyze the correlations between variables. It was observed no differences between groups for the markers of muscle damage, although significant modifications (p < 0.05) occurred within groups throughout time for all variables. Post menopausal women showed significantly higher values for TNF-α (p < 0.05). Also, IL-6 presented superior pre value for PMW. For YW, IL-6 and IL-10 values increased 72 h post-eccentric exercise compared to pre. Further, IL-10 was higher for YW than PMW 72 h post-eccentric exercise. Significant correlations (p < 0.05) were found between age and soreness, and between age and PGE(2). In conclusion, YW do not have attenuated muscle damage compared to PMW who do not make use of hormonal replacement therapy. In addition, YW have a greater anti-inflammatory response after eccentric exercise compared to PMW.en
dc.relation.ispartofEuropean Journal Of Applied Physiologypt_BR
dc.relation.ispartofabbreviationEur. J. Appl. Physiol.pt_BR
dc.date.issued2012-Seppt_BR
dc.identifier.citationEuropean Journal Of Applied Physiology. v. 112, n. 9, p. 3205-13, 2012-Sep.pt_BR
dc.language.isoengpt_BR
dc.description.volume112pt_BR
dc.description.firstpage3205-13pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1439-6327pt_BR
dc.identifier.doi10.1007/s00421-011-2292-6pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/22227852pt_BR
dc.date.available2015-11-27T13:28:07Z-
dc.date.accessioned2015-11-27T13:28:07Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:28:07Z (GMT). No. of bitstreams: 1 pmed_22227852.pdf: 352906 bytes, checksum: 8b0b5ca34423afb246905fe55e8c3c19 (MD5) Previous issue date: 2012en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199833-
dc.identifier.idPubmed22227852pt_BR
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