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Type: Artigo de periódico
Title: Ingestion Of Polydextrose Increase The Iron Absorption In Rats Submitted To Partial Gastrectomy.
Author: Santos, Elisvânia Freitas dos
Tsuboi, Kathia Hitomi
Araújo, Marina Rachel
Falconi, Mônica Almeida
Ouwehand, Arthur C
Andreollo, Nelson Adami
Miyasaka, Celio Kenji
Abstract: To investigate whether polydextrose stimulates iron absorption in rats submitted to partial gastrectomy and sham operated. The rats were submitted to partial gastrectomy (Billroth II) or laparotomy (sham-operated control), in groups of 20 and 20 each respectively. The animals were fed with a control diet (AIN-93M) without polydextrose or a diet containing polydextrose (50g/Kg of diet) for eight weeks. They were divided into four subgroups: sham-operated and Billroth II gastrectomy and with or without polydextrose. Two animals died during the experiment. All rats submitted to gastrectomy received B-12 vitamin (intramuscular) each two weeks. The hematocrit and hemoglobin concentration were measured at the start and on day 30 and 56 after the beginning of the experimental period. At the end of the study, the blood was collected for determination of serum iron concentration. The diet with polydextrose reduced the excretion of iron. Apparent iron absorption was higher in the polydextrose fed groups than in the control group. The haematocrit and haemoglobin concentration were lower after Billroth II gastrectomy rats fed the control diet as compared to the polydextrose diet groups. Polydextrose increase iron absorption and prevents postgastrectomy anemia.
Subject: Analysis Of Variance
Body Weight
Intestinal Absorption
Random Allocation
Rats, Wistar
Citation: Acta Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia. v. 25, n. 6, p. 518-24, 2010-Dec.
Rights: aberto
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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