Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198726
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleLeptin And Adiponectin Blood Levels In Women With Premature Ovarian Failure And Age- And Weight-matched Women With Normal Menstrual Cycles.pt_BR
dc.contributor.authorBenetti-Pinto, Cristina Lagunapt_BR
dc.contributor.authorCastro, Natáliapt_BR
dc.contributor.authorGrassiotto, Oswaldo da Rochapt_BR
dc.contributor.authorGarmes, Heraldo Mendespt_BR
unicamp.authorCristina Laguna Benetti-Pinto, Division of Gynecology Endocrinology, Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil. crislag@sigmanet.com.brpt_BR
unicamp.author.externalNatália Castro,pt
unicamp.author.externalOswaldo da Rocha Grassiotto,pt
unicamp.author.externalHeraldo Mendes Garmes,pt
dc.subjectAdiponectinpt_BR
dc.subjectAdultpt_BR
dc.subjectBody Mass Indexpt_BR
dc.subjectBody Weightpt_BR
dc.subjectCase-control Studiespt_BR
dc.subjectCross-sectional Studiespt_BR
dc.subjectFemalept_BR
dc.subjectHumanspt_BR
dc.subjectLeptinpt_BR
dc.subjectPrimary Ovarian Insufficiencypt_BR
dc.description.abstractThe aim of this study was to evaluate leptin and adiponectin blood levels in women with premature ovarian failure (POF) and women with a normal menstrual cycle. This was a cross-sectional study involving 60 women divided into two groups: the study group (G1) comprising 30 women with POF not receiving hormone therapy for at least 3 months and the control group (G2) comprising 30 women with a normal menstrual cycle. Both groups were age and body mass index (BMI) matched. Study participants had a mean (+/-SD) age of 34.4 (+/-5.3) and 34.2 (+/-5.6) years and mean BMI (+/-SD) of 24.7 (+/-6.3) and 24.5 (+/-4.6) kg/m in G1 and G2, respectively. Serum leptin levels were significantly lower in G1 compared with G2 (8.8 +/- 12.2 and 12.2 +/- 9.7 ng/mL; P < 0.05). Serum adiponectin levels were similar in both groups. Leptin levels were positively correlated to weight (r = 0.38; P = 0.03) but were not correlated to BMI and age in women with POF (G1); in G2, they were positively correlated to BMI (r = 0.59; P = 0.0006), weight (r = 0.63; P = 0.0006), and age (r = 0.40; P = 0.02). Adiponectin levels did not correlate to weight, BMI, or age in both groups. These results suggest that gonadal function loss may decrease leptin circulating levels, independently from age and BMI. Adiponectin seems not to correlate to hormonal status.en
dc.relation.ispartofMenopause (new York, N.y.)pt_BR
dc.relation.ispartofabbreviationMenopausept_BR
dc.identifier.citationMenopause (new York, N.y.). v. 17, n. 1, p. 174-7pt_BR
dc.language.isoengpt_BR
dc.description.volume17pt_BR
dc.description.firstpage174-7pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1530-0374pt_BR
dc.identifier.doi10.1097/gme.0b013e3181b00dadpt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/19609224pt_BR
dc.date.available2015-11-27T13:17:34Z-
dc.date.accessioned2015-11-27T13:17:34Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:17:34Z (GMT). No. of bitstreams: 0 Previous issue date: nullen
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198726-
dc.identifier.idPubmed19609224pt_BR
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