Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198686
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleCompartment Syndrome After Bothrops Jararaca Snakebite: Monitoring, Treatment, And Outcome.pt_BR
dc.contributor.authorBucaretchi, Fábiopt_BR
dc.contributor.authorde Capitani, Eduardo Mellopt_BR
dc.contributor.authorHyslop, Stephenpt_BR
dc.contributor.authorMello, Sueli Moreirapt_BR
dc.contributor.authorMadureira, Paulo Robertopt_BR
dc.contributor.authorZanardi, Veronicapt_BR
dc.contributor.authorFerreira, Daniel Mpt_BR
dc.contributor.authorMeirelles, Guilerme Vpt_BR
dc.contributor.authorFernandes, Luciane C Rpt_BR
unicamp.authorFábio Bucaretchi, Faculty of Medical Sciences, State University of Campinas, Pediatrics and Poison Control Center, Campinas, Brazil. bucaret@fcm.unicamp.brpt_BR
unicamp.author.externalEduardo Mello de Capitani,pt
unicamp.author.externalStephen Hyslop,pt
unicamp.author.externalSueli Moreira Mello,pt
unicamp.author.externalPaulo Roberto Madureira,pt
unicamp.author.externalVeronica Zanardi,pt
unicamp.author.externalDaniel M Ferreira,pt
unicamp.author.externalGuilerme V Meirelles,pt
unicamp.author.externalLuciane C R Fernandes,pt
dc.subjectAnimalspt_BR
dc.subjectAntiveninspt_BR
dc.subjectBacterial Infectionspt_BR
dc.subjectBiological Markerspt_BR
dc.subjectBothropspt_BR
dc.subjectCompartment Syndromespt_BR
dc.subjectCrotalid Venomspt_BR
dc.subjectEnzyme-linked Immunosorbent Assaypt_BR
dc.subjectHumanspt_BR
dc.subjectMagnetic Resonance Imagingpt_BR
dc.subjectMalept_BR
dc.subjectMiddle Agedpt_BR
dc.subjectMonitoring, Physiologicpt_BR
dc.subjectPainpt_BR
dc.subjectPressurept_BR
dc.subjectSnake Bitespt_BR
dc.subjectTreatment Outcomept_BR
dc.description.abstractTo report the outcome of a patient who developed compartment syndrome after Bothrops jararaca snakebite. A 39-year-old male was admitted 5 h after being bitten on the lower right leg. Physical examination revealed tense swelling, ecchymosis, hypoesthesia, and intense local pain that worsened after passive stretching, limited right foot dorsiflexion, and gingival bleeding. The case was classified as moderate/severe and eight vials of bothropic antivenom (AV) were infused 1 h postadmission. The main laboratory findings upon admission were incoagulable blood (incoagulable PT, aPTT, and INR), thrombocytopenia, serum creatine kinase (CK) of 580 U/L (reference value < 170 U/L), and a serum venom level of 33.7 ng/mL (ELISA; cutoff = 2.3 ng/mL). High anterior compartment pressure (60 mmHg) was identified 8 h post bite, with progressively lower pressures after AV administration and limb elevation (36 mmHg; 19 h post bite). However, moderate pain and limited foot dorsiflexion persisted. In addition, there was a progressive increase in serum CK (6,729 U/L; 45 h post bite), as well as marked edema and hemorrhage of the anterior compartment detected by magnetic resonance imaging (MRI) at 48 h post bite. A fasciotomy done after a further increase in intracompartmental pressure (66 mmHg, 57 h post bite) revealed hemorrhage/necrosis of the anterior tibial muscle that subsequently required partial resection. The patient developed a local infection (day 15 post bite) and a permanent fibular palsy. Compartment syndrome is an unusual but severe complication of snakebites. MRI, in conjunction with subfascial pressure measurements, may be useful in the diagnosis of compartment syndrome after snakebites.en
dc.relation.ispartofClinical Toxicology (philadelphia, Pa.)pt_BR
dc.relation.ispartofabbreviationClin Toxicol (Phila)pt_BR
dc.date.issued2010-Janpt_BR
dc.identifier.citationClinical Toxicology (philadelphia, Pa.). v. 48, n. 1, p. 57-60, 2010-Jan.pt_BR
dc.language.isoengpt_BR
dc.description.volume48pt_BR
dc.description.firstpage57-60pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1556-9519pt_BR
dc.identifier.doi10.3109/15563650903356201pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/20095815pt_BR
dc.date.available2015-11-27T13:17:27Z-
dc.date.accessioned2015-11-27T13:17:27Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:17:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2010en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198686-
dc.identifier.idPubmed20095815pt_BR
Appears in Collections:Unicamp - Artigos e Outros Documentos

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