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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleMri Shows Dorsal Lesions And Spinal Cord Atrophy In Chronic Sensory Neuronopathies.pt_BR
dc.contributor.authorFrança, Marcondes Cpt_BR
dc.contributor.authorD'Abreu, Anelyssapt_BR
dc.contributor.authorZanardi, Verônica Apt_BR
dc.contributor.authorFaria, Andréia Vpt_BR
dc.contributor.authorLopes-Cendes, Isciapt_BR
dc.contributor.authorNucci, Anamarlipt_BR
dc.contributor.authorCendes, Fernandopt_BR
unicamp.authorMarcondes C França, Department of Neurology, Campinas State University (UNICAMP), Campinas, Brazil.pt_BR
unicamp.author.externalAnelyssa D'Abreu,pt
unicamp.author.externalVerônica A Zanardi,pt
unicamp.author.externalAndréia V Faria,pt
unicamp.author.externalIscia Lopes-Cendes,pt
unicamp.author.externalAnamarli Nucci,pt
unicamp.author.externalFernando Cendes,pt
dc.subjectAnalysis Of Variancept_BR
dc.subjectAtrophypt_BR
dc.subjectCase-control Studiespt_BR
dc.subjectChronic Diseasept_BR
dc.subjectFemalept_BR
dc.subjectHereditary Sensory And Autonomic Neuropathiespt_BR
dc.subjectHumanspt_BR
dc.subjectImage Processing, Computer-assistedpt_BR
dc.subjectLinear Modelspt_BR
dc.subjectMagnetic Resonance Imagingpt_BR
dc.subjectMalept_BR
dc.subjectMiddle Agedpt_BR
dc.subjectSpinal Cordpt_BR
dc.description.abstractSensory neuronopathies (SN) represent a specific subgroup of peripheral nervous system diseases, characterized by degeneration of dorsal root ganglia (DRG) and its projections. We tried to estimate the frequency and extent of spinal cord MRI abnormalities in a group of patients with SN and correlate these with clinical and neurophysiological features. We performed spinal cord MRI scans in 16 chronic SN patients. Images were analyzed for the presence of posterior hyperintense lesions on T2WI and cord areas at C3 level were obtained using a previously validated method. A group of 14 healthy controls with similar age and gender distribution was used for comparison. ANOVA was employed for statistical analysis. Posterior T2WI lesions were found in 13 out of 16 patients. Cord areas were significantly smaller in SN patients than controls (84.3 x 97.2 mm(2), P < .05). Atrophy correlated with severity of sensory ataxia and neurophysiologic abnormalities but not with duration of disease. These findings support volumetric spinal cord MRI as a useful tool in the assessment of chronic SN.en
dc.relation.ispartofJournal Of Neuroimaging : Official Journal Of The American Society Of Neuroimagingpt_BR
dc.relation.ispartofabbreviationJ Neuroimagingpt_BR
dc.date.issued2008-Aprpt_BR
dc.identifier.citationJournal Of Neuroimaging : Official Journal Of The American Society Of Neuroimaging. v. 18, n. 2, p. 168-72, 2008-Apr.pt_BR
dc.language.isoengpt_BR
dc.description.volume18pt_BR
dc.description.firstpage168-72pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1051-2284pt_BR
dc.identifier.doi10.1111/j.1552-6569.2007.00193.xpt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/18380696pt_BR
dc.date.available2015-11-27T13:12:39Z-
dc.date.accessioned2015-11-27T13:12:39Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:12:39Z (GMT). No. of bitstreams: 1 pmed_18380696.pdf: 545657 bytes, checksum: cb3b3446d439a2b327b327afb0f0afc4 (MD5) Previous issue date: 2008en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197732-
dc.identifier.idPubmed18380696pt_BR
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