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Type: Artigo de periódico
Title: Fatal Disseminated Paracoccidioidomycosis In A Two-year-old Child.
Author: Pereira, Ricardo M
Tresoldi, Antonia Terezinha
da Silva, Marcus T N
Bucaretchi, Fábio
Abstract: A two year-old female child was admitted at the Pediatric Intensive Care Unit in a septic shock associated with a lymphoproliferative syndrome, with history of fever, adynamia and weight loss during the last two months. On admission, the main clinical and laboratory manifestations were: pallor, jaundice, disseminated enlarged lymph nodes, hepatosplenomegaly, crusted warts on face, anemia, eosinophilia, thrombocytopenia, increased direct and indirect bilirubin, alkaline phosphatase, and gammaglutamyl transpeptidase. A parenteral administration of fluids, dobutamine and mechanical ventilation was started, without improvement of the clinical conditions. A direct examination of exsudate collected from cervical lymph node revealed numerous oval-to-around cells with multiple budding, like a pilot wheel cell, suggesting Paracoccidioides brasiliensis. Even though treatment with intravenous sulfamethoxazole-trimethoprine was soon started, the child died 36 hours after hospital admission. Disseminated paracoccidioidomycosis was confirmed in the autopsy. This is the youngest case of paracoccidioidomycosis in children reported in the literature.
Subject: Child
Fatal Outcome
Lymphoproliferative Disorders
Shock, Septic
Citation: Revista Do Instituto De Medicina Tropical De São Paulo. v. 46, n. 1, p. 37-9
Rights: aberto
Appears in Collections:Unicamp - Artigos e Outros Documentos

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