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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleAbo Blood Group In Amerindians From Brazilian Amazon.pt_BR
dc.contributor.authorBarjas-Castro, M Lpt_BR
dc.contributor.authorSoares, M C Ppt_BR
dc.contributor.authorMenezes, R Cpt_BR
dc.contributor.authorCarvalho, M H Mpt_BR
dc.contributor.authorCosta, F Fpt_BR
dc.contributor.authorSaad, S T Opt_BR
unicamp.authorM L Barjas-Castro, Centro de Hematologia e Medicina Transfusional, Universidade Estadual de Campinas, UNICAMP, São Paulo, Brazil. maluz@unicamp.brpt_BR
unicamp.author.externalM C P Soares,pt
unicamp.author.externalR C Menezes,pt
unicamp.author.externalM H M Carvalho,pt
unicamp.author.externalF F Costa,pt
unicamp.author.externalS T O Saad,pt
dc.subjectAbo Blood-group Systempt_BR
dc.subjectAdolescentpt_BR
dc.subjectAdultpt_BR
dc.subjectAgedpt_BR
dc.subjectBrazilpt_BR
dc.subjectChildpt_BR
dc.subjectDnapt_BR
dc.subjectEthnic Groupspt_BR
dc.subjectFemalept_BR
dc.subjectGene Deletionpt_BR
dc.subjectGene Frequencypt_BR
dc.subjectHumanspt_BR
dc.subjectMalept_BR
dc.subjectMiddle Agedpt_BR
dc.subjectMutationpt_BR
dc.subjectPolymerase Chain Reactionpt_BR
dc.subjectPolymorphism, Geneticpt_BR
dc.description.abstractThe Parakanã is a group of Indians with cultural similarities to the extinct Tupi group. They are an isolated native population from East Brazilian Amazon. A number of different O alleles have been found at the blood group ABO locus in populations of several ethnic origins (Caucasians, Blacks, Amerindians). The present study describes the ABO blood group polymorphism gene of the Parakanã Indians. The Amerindian group was carefully selected for racial background. The blood group polymorphism was analysed in genomic DNA from 62 Parakanã Indians. We determined the 261G deletion, the T646A and C771T mutations described in O(1variant) and the G542A substitution, using PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism). All Amerindians studied were homozygous for the 261G deletion. The frequencies of the T646A and C771T mutations in Parakanãs (0.65) were lower than that observed in Kayapo, Yanomama and Arara Indians (0.91) (chi (2) = 18.24; p-v < 0.001. The G542A substitution in Parakanãs was also lower (0.22) than in other tribes (0.42) (chi(2) = 9.73; p-v = 0.001). The different O alleles including the G542A mutation are not distributed homogeneously among all Amazonian Amerindians. Our results are in agreement with other genetic markers studied previously in Parakanã Indians, whose distinct genetic pattern differs from Europeans and even from other Amerindians.en
dc.relation.ispartofAnnals Of Human Biologypt_BR
dc.relation.ispartofabbreviationAnn. Hum. Biol.pt_BR
dc.identifier.citationAnnals Of Human Biology. v. 30, n. 2, p. 220-4pt_BR
dc.language.isoengpt_BR
dc.description.volume30pt_BR
dc.description.firstpage220-4pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0301-4460pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/12637197pt_BR
dc.date.available2015-11-27T12:52:44Z-
dc.date.accessioned2015-11-27T12:52:44Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:52:44Z (GMT). No. of bitstreams: 1 pmed_12637197.pdf: 184090 bytes, checksum: 25e2d97076375711d36f37172e96a38a (MD5) Previous issue date: nullen
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195693-
dc.identifier.idPubmed12637197pt_BR
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