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Type: Artigo de periódico
Title: [use Of Corticosteroids After Esophageal Dilations On Patients With Corrosive Stenosis: Prospective, Randomized And Double-blind Study].
Author: Camargo, Marcelo Amade
Lopes, Luiz Roberto
Grangeia, Tiago de Araújo Guerra
Andreollo, Nelson Adami
Brandalise, Nelson Ary
Abstract: To determine triancinolone intralesional injections effects in association with esophageal dilations in corrosive stenosis cases, by means of a double-blind and randomized study. Fourteen adults patients (6 men and 8 women) with severe esophageal corrosive stenosis were randomized in two groups: Group A: treated by esophageal dilations and posterior triancinolone 10 mg/ml intralesional injection; Group B: treated by esophageal injections and posterior saline solution 0,9% injection (placebo). New applications were made based on the patient symptomatology. It had been analysed dilation frequency, obtained diameters and dysphagia before and after the research, for 12 months. Eleven patients had ingested sodium hydroxide, two had ingested ammoniac and one had taken muriatic acid. There was no statistic difference (p > 0.05) in dilation frequency and dysphagia between the groups. However, an improvement in obtained diameter was observed in the corticosteroids group in comparison with control group (p < 0.05). By comparing groups before and after steroids, the final results were very favorable in group A CONCLUSION: Multiple intralesional injections of triancinolone hexacetonide 10 mg/ml in association with esophageal dilations increase obtained diameters in succeeding sessions.
Subject: Adult
Anti-inflammatory Agents
Burns, Chemical
Combined Modality Therapy
Double-blind Method
Esophageal Stenosis
Follow-up Studies
Injections, Intralesional
Middle Aged
Prospective Studies
Severity Of Illness Index
Treatment Outcome
Triamcinolone Acetonide
Citation: Revista Da Associação Médica Brasileira (1992). v. 49, n. 3, p. 286-92
Rights: fechado
Appears in Collections:Unicamp - Artigos e Outros Documentos

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