Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194418
Type: Artigo de periódico
Title: The Epiphyseal Cartilage And Growth Of Long Bones In Rana Catesbeiana.
Author: Felisbino, S L
Carvalho, H F
Abstract: The structure of the epiphyseal cartilage of the bullfrog Rana catesbeiana and its role in the growth of long bones were examined. The epiphyseal cartilage was inserted into the end of a tubular bone shaft, defining three regions: articular cartilage, lateral articular cartilage and growth cartilage. Joining the lateral cartilage to the bone was a fibrous layer of periosteum, rich in blood vessels. Osteoblasts with alkaline phosphatase activity were found on the surface of the periosteal bone, which presented a fibrous non-mineralised tip. The growth cartilage was inside the bone. The proliferative chondrocytes presented perpendicular separation of daughter cells and there was no columnar arrangement of the cells. Furthermore, chondrocyte hypertrophy was not associated with either calcification or endochondral ossification, in apparent contrast to the avian and mammalian models. Finally, there was no reinforcement system capable of directing cell volume increase into longitudinal growth. Since bone extension depends on the intramembranous ossification of the periosteum, the growth cartilage is inside and not at the end of the bone and the cells in the growth cartilage show no columnar arrangement and separate in a direction perpendicular to the long bone axis, we conclude that the growth cartilage mainly contributes to the radial expansion of the bone.
Subject: Animals
Female
Growth Plate
Male
Microscopy, Electron
Osteoblasts
Periosteum
Rana Catesbeiana
Citation: Tissue & Cell. v. 31, n. 3, p. 301-7, 1999-Jun.
Rights: fechado
Identifier DOI: 10.1054/tice.1999.0036
Address: http://www.ncbi.nlm.nih.gov/pubmed/10481302
Date Issue: 1999
Appears in Collections:Unicamp - Artigos e Outros Documentos

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