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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.title[brain Aging. The Problem Of Differential Diagnosis Between Normal And Pathologic].pt_BR
dc.contributor.authorDamasceno, B Ppt_BR
unicamp.authorB P Damasceno, Departamento de Neurologia, Faculdade de Ciências Médicas (FCM), Universidade Estadual de Campinas (UNICAMP), Brasil. damescen@turing.unicamp.brpt_BR
dc.subjectAgedpt_BR
dc.subjectAgingpt_BR
dc.subjectBrainpt_BR
dc.subjectDementiapt_BR
dc.subjectDiagnosis, Differentialpt_BR
dc.subjectFemalept_BR
dc.subjectHumanspt_BR
dc.subjectMiddle Agedpt_BR
dc.subjectNeuropsychological Testspt_BR
dc.description.abstractThe author reports three cases of pseudodementia and discuss the difficulties in establishing limits between normality and illness in the elderly. The mental and neuropathological changes that accompany the normal ageing of the brain are similar to those of early Alzheimer's dementia (AD). These similarities often lead to difficulties in the differential diagnosis, hence the search for consensus criteria. The decline of working and secondary memory is greater than that of primary and tertiary memory, as is found in AD. On the other hand, tests of delayed recall of 10 to 15 unrelated words, logical memory, categorical thinking, visuo-motor-spatial skills, and Boston Naming Test have been pointed out as the most discriminative. Neuroimaging findings of atrophy or hypoperfusion in the entorhinal-hippocampal or temporo-parietal regions are suggestive of DA, but they can be lacking in the early stages of this disease. In the conclusion, the author suggests the diagnostic process should be based on a comprehensive neuropsychological and behavioral evaluation (including a survey of the subject's premorbid level of cognitive and socio-occupational functioning), supplemented by neuroimaging and laboratory tests. If inconclusive, the whole evaluation can be repeated after 4 to 6 months, to check the consistency of the findings.en
dc.relation.ispartofArquivos De Neuro-psiquiatriapt_BR
dc.relation.ispartofabbreviationArq Neuropsiquiatrpt_BR
dc.date.issued1999-Marpt_BR
dc.identifier.citationArquivos De Neuro-psiquiatria. v. 57, n. 1, p. 78-83, 1999-Mar.pt_BR
dc.language.isoporpt_BR
dc.description.volume57pt_BR
dc.description.firstpage78-83pt_BR
dc.rightsabertopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0004-282Xpt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/10347729pt_BR
dc.date.available2015-11-27T12:19:36Z-
dc.date.accessioned2015-11-27T12:19:36Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:19:36Z (GMT). No. of bitstreams: 0 Previous issue date: 1999en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194365-
dc.identifier.idPubmed10347729pt_BR
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