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Type: Artigo de periódico
Title: Fatty Acid-mediated Uncoupling Of Potato Tuber Mitochondria.
Author: Saviani, E E
Martins, I S
Abstract: The present work examined whether the ATP/ADP carrier, other than the plant uncoupling mitochondrial protein, participates in free fatty acid-mediated uncoupling of potato tuber mitochondria. The basal respiration rate of succinate-energized mitochondria was stimulated by a low concentration of palmitate (20 microM). This uncoupling was reversed by 10 microM carboxyatractyloside and by the subsequent addition of 0.1% bovine serum albumin. The decrease in membrane potential caused by palmitate was suppressed by carboxyatractyloside (1 microM) and, to a lesser degree, by bongkrekate (20 microM). GTP could also reversed this decrease via a carboxyatractyloside-independent mechanism. These results indicate that the ATP/ADP carrier, along with the plant uncoupling mitochondrial protein, participates in the protonophoric action of palmitate in potato tuber mitochondria.
Subject: Atractyloside
Carrier Proteins
Fatty Acids, Nonesterified
Intracellular Membranes
Ion Channels
Membrane Potentials
Membrane Proteins
Mitochondrial Proteins
Oxygen Consumption
Plant Proteins
Receptors, Cytoplasmic And Nuclear
Serum Albumin, Bovine
Solanum Tuberosum
Citation: Biochemistry And Molecular Biology International. v. 44, n. 4, p. 833-9, 1998-Apr.
Rights: fechado
Date Issue: 1998
Appears in Collections:Unicamp - Artigos e Outros Documentos

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