Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/193847
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleInsulin Resistance In Psoriasis.pt_BR
dc.contributor.authorBrenelli, S Lpt_BR
dc.contributor.authorMoraes, A Mpt_BR
dc.contributor.authorMonte-Alegre, Spt_BR
dc.contributor.authorCarvalho, O Mpt_BR
dc.contributor.authorSaad, M Jpt_BR
unicamp.authorS L Brenelli, Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, SP, Brasil.pt_BR
unicamp.author.externalA M Moraes,pt
unicamp.author.externalS Monte-Alegre,pt
unicamp.author.externalO M Carvalho,pt
unicamp.author.externalM J Saad,pt
dc.subjectAdultpt_BR
dc.subjectBlood Glucosept_BR
dc.subjectFemalept_BR
dc.subjectGlucose Tolerance Testpt_BR
dc.subjectHumanspt_BR
dc.subjectInsulinpt_BR
dc.subjectInsulin Resistancept_BR
dc.subjectMalept_BR
dc.subjectPsoriasispt_BR
dc.description.abstractThe oral glucose tolerance test (OGTT) and intravenous insulin tolerance test (15-min ITT) were applied to ten patients with psoriasis and to 11 control subjects. No significant differences in mean plasma glucose levels were detected between psoriatic patients and normal individuals. In contrast, serum insulin levels were significantly higher for the psoriatic patients as compared to the controls at 30, 60 and 120 min during the OGTT (P < 0.05). The glucose disappearance rate during the 15-min ITT was lower in patients with psoriasis than in controls (5.1 +/- 0.5%/min vs 7.5 +/- 0.4%/min, P < 0.05), demonstrating a state of insulin resistance. Interestingly, the reduction in serum potassium levels during the ITT was also lower in the patients than in the controls (0.6 +/- 0.06 mEq/l vs 1.06 +/- 0.07 mEq/l, P < 0.05), suggesting that the insulin resistance observed in psoriasis is not only related to glucose metabolism, but also to another important action of insulin, namely extrarenal potassium homeostasis.en
dc.relation.ispartofBrazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]pt_BR
dc.relation.ispartofabbreviationBraz. J. Med. Biol. Res.pt_BR
dc.date.issued1995-Marpt_BR
dc.identifier.citationBrazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]. v. 28, n. 3, p. 297-301, 1995-Mar.pt_BR
dc.language.isoengpt_BR
dc.description.volume28pt_BR
dc.description.firstpage297-301pt_BR
dc.rightsabertopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0100-879Xpt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/8520522pt_BR
dc.date.available2015-11-27T12:18:37Z-
dc.date.accessioned2015-11-27T12:18:37Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:18:37Z (GMT). No. of bitstreams: 0 Previous issue date: 1995en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/193847-
dc.identifier.idPubmed8520522pt_BR
Appears in Collections:Unicamp - Artigos e Outros Documentos

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