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Type: Artigo de periódico
Title: Hematological Phenotype And The Type Of β Thalassemia Mutation In Brazil
Author: Bertuzzo C.S.
Sonati M.F.
Costa F.F.
Abstract: The type of β thalassemia mutation found in heterozygous individuals is believed to influence hematological symptoms. Our data demonstrated that patients with the mild mutation (β IVSI-nt 6) have a higher mean corpuscular hemoglobin (MCH) than those with the severe forms (β(o)39 or β IVSI-nt 1), and the hemoglobin A2 levels were lower in β(o) mutations than in the β IVSI-nt 6 mutation. However, in contrast to previous studies, we were not able to indicate MCH as a clear discriminator between the β(o) and β+ mutations.
Citation: Brazilian Journal Of Genetics. , v. 20, n. 2, p. 319 - 321, 1997.
Rights: aberto
Date Issue: 1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

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